Green Coffee Bean Extract
Product Description
Product Name: Green Coffee Bean Extract
Category: Bean
Effective components: Chlorogenic Acid
Product specification: 25% 50%
Analysis: HPLC
Quality Control: In House
Formulate: C16H18O9
Molecular weight: 354.31
CAS No: 327-97-9
Appearance: Brownish yellow powder with characteristic odor
Identification: Passes all criteria tests
What is Green Coffee Bean?
Green coffee bean, scientifically known as Coffea canephora robusta, are raw coffee bean, meaning they do not undergo a roasting process.
Perhaps the most prominent benefit of green coffee is weight loss, and green coffee extract (GCE) is a key weight loss supplement.
Green coffee bean extract is extracted from the seeds of the small-fruited coffee, medium-fruited coffee, and large-fruited coffee plants of the Rubiaceae family, with chlorogenic acid as the main active substance, and also contains alkaloids such as caffeine and fenugreek alkaloids. Chlorogenic acid is a phenylpropanoid compound produced by the plant in the process of aerobic respiration through the shikimic acid pathway, with antibacterial, antiviral, increase white blood cells, hepatoprotective and choleretic, antitumor, hypotensive, hypolipidemic, scavenging free radicals and stimulating the central nervous system and other effects. The right amount of caffeine will stimulate the cerebral cortex, promote sensory judgment, memory, and emotional activity, so that the heart muscle function becomes more active, blood vessel dilation and blood circulation is enhanced, and improve metabolic function, caffeine can also reduce muscle fatigue, promote the secretion of digestive juices. However, large doses or long-term use can also cause damage to the human body, which can cause paroxysmal convulsions, and damage to the liver, stomach, kidneys, and other important internal organs. Green coffee bean extract is very widely used, mainly in the pharmaceutical, daily chemical, and food industries.
Further benefits of green coffee:
However, the positive effects of green coffee are not limited to maintaining extra weight. Not only is it an effective and accessible weight loss aid, but it also offers the following scientifically backed benefits.
Skin health - Green coffee contains high levels of volatile substances that maintain healthy, glowing skin as well as reduce the appearance of wrinkles. When used on the skin of animal models, it shows high antioxidant and anti-inflammatory activity.
Blood pressure reduction- The prominent chlorogenic acid in green coffee is believed to be effective in lowering blood pressure and may provide a safe tool for patients with mild hypertension.
Muscle injury protection- The use of green as well as mature coffee may play a role in protecting against muscle injury after exercise. In addition, it may reduce the percentage of visceral fat, thus preventing further complications once this tissue produces pathogenic hormones.
Fight against metabolic syndrome - GCE supplementation has a favorable effect on glycemic control, lipid profile, blood pressure, and insulin resistance indicators in patients with metabolic syndrome. Combined with green tea extract, it also has beneficial effects on improving metabolic syndrome by affecting related gene expression.
Neuroprotection - Green coffee has been found to have a neuroprotective effect on insulin resistance-induced Alzheimer's disease. It has been reported to attenuate insulin resistance and improve energy metabolism, potentially delaying the onset or hindering the progression of Alzheimer's disease., and it has been shown to have a beneficial effect on the development of Alzheimer's disease.
Pharmacological effects:
1. Antioxidant, the scavenging effect of free radicals in the body Green coffee bean extract has a strong total antioxidant capacity in a certain concentration range, strong DPPH free radical scavenging activity, and strong iron ion reducing ability, but not metal ion chelating ability. Green coffee bean extract has strong antioxidant activity and is a potent natural antioxidant.
2. antibacterial, antiviral effect chlorogenic acid has antiviral and hemostatic, increases white blood cells, shortens the blood clotting and bleeding time, and other effects. Chlorogenic acid has significant inhibitory and killing effects on a variety of pathogenic bacteria, such as Staphylococcus aureus, hemolytic streptococcus, dysentery cocci, typhoid bacillus, pneumococcus, etc. Chlorogenic acid has an obvious effect on acute throat inflammation and skin diseases and is clinically used to treat acute bacterial infectious diseases.
3. Anti-mutation, anti-tumor effect chlorogenic acid has a strong mutagenic ability, can inhibit the mutation caused by aflatoxin B and the mutation caused by sub-digestion reaction, and can effectively reduce the γ-ray-induced bone marrow erythrocyte mutation; chlorogenic acid can reduce the utilization of carcinogens and its transport in the liver to achieve the effect of cancer prevention, anti-cancer. Chlorogenic acid has a significant inhibitory effect on colorectal cancer, liver cancer, and laryngeal cancer, and is considered an effective chemoprotective agent against cancer.
4. Cardiovascular protection Chlorogenic acid as a free radical scavenger and antioxidant has been extensively tested to prove that this biological activity of chlorogenic acid can have a protective effect on the cardiovascular system. By scavenging free radicals and anti-lipid peroxidation, chlorogenic acid can protect vascular endothelial cells, which in turn can play a role in the prevention of atherosclerosis, thromboembolic diseases, and hypertension.
5. Other effects Chlorogenic acid and its derivatives have shown some inhibitory effects in anti-HIV studies, and chlorogenic acid has special inhibitory effects on HAase and glucose xun-monophosphatase, and has certain effects on wound healing, skin moisturizing, joint lubrication, and inflammation prevention. Oral administration of chlorogenic acid can significantly stimulate the secretion of bile, with a cholorogenic effect; chlorogenic acid also has a significant inhibitory effect on the gastric ulcer, and it can also effectively inhibit H202-induced erythrocyte hemolysis in rats.
Certificate of Analysis
| Product name | Green Coffee Bean Extract | Botanical Source | Coffea L |
| Batch NO. | RW-GCB20210508 | Batch Quantity | 1000 kgs |
| Manufacture Date | May. 08. 2021 | Inspection Date | May. 17. 2021 |
| Solvents Residue | Water&Ethanol | Part Used | Bean |
| ITEMS | SPECIFICATION | METHOD | TEST RESULT |
| Physical&Chemical Data | |||
| Color | Brownish yellow powder | Organoleptic | Qualified |
| Ordour | Characteristic | Organoleptic | Qualified |
| Appearance | Fine Powder | Organoleptic | Qualified |
| Analytical Quality | |||
| Identification | Identical to R.S. sample | HPTLC | Identical |
| Chlorogenic Acid | ≥50.0% | HPLC | 51.63% |
| Loss on Drying | 5.0% Max. | Eur.Ph.7.0 [2.5.12] | 3.21% |
| Total Ash | 5.0% Max. | Eur.Ph.7.0 [2.4.16] | 3.62% |
| Sieve | 100% pass 80 mesh | USP36<786> | Conform |
| Loose Density | 20~60 g/100ml | Eur.Ph.7.0 [2.9.34] | 53.38 g/100ml |
| Tap Density | 30~80 g/100ml | Eur.Ph.7.0 [2.9.34] | 72.38 g/100ml |
| Solvents Residue | Meet Eur.Ph.7.0 <5.4> | Eur.Ph.7.0 <2.4.24> | Qualified |
| Pesticides Residue | Meet USP Requirements | USP36 <561> | Qualified |
| Heavy Metals | |||
| Total Heavy Metals | 10ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 1.388g/kg |
| Lead (Pb) | 3.0ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.062g/kg |
| Arsenic (As) | 2.0ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.005g/kg |
| Cadmium(Cd) | 1.0ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.005g/kg |
| Mercury (Hg) | 0.5ppm Max. | Eur.Ph.7.0 <2.2.58> ICP-MS | 0.025g/kg |
| Microbe Tests | |||
| Total Plate Count | NMT 1000cfu/g | USP <2021> | Qualified |
| Total Yeast & Mold | NMT 100cfu/g | USP <2021> | Qualified |
| E.Coli | Negative | USP <2021> | Negative |
| Salmonella | Negative | USP <2021> | Negative |
| Packing&Storage | Packed in paper-drums and two plastic-bags inside. | ||
| N.W: 25kgs | |||
| Store in a well-closed container away from moisture, light, oxygen. | |||
| Shelf life | 24 months under the conditions above and in its original packaging. | ||
Analyst: Dang Wang
Checked by: Lei Li
Approved by: Yang Zhang
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Product Function
Green Coffee Beans for weight loss reduce free oxygen,reducing blood fat,protect kidney,slimming weight loss,food supplements,Significant antihypertensive effect, and non-toxic side effects and smooth; Remarkable prevention and treatment of nasopharyngeal carcinoma effect,has the remarkable tumor therapy efficacy, and have low toxicity and safe characteristic; Protect kidney and enhance the immune function; Resist oxidation, aging, and resist bone-aging; Antibacterial, antiviral, diuresis, cholagogue, reducing blood fat, and prevent miscarriage; clearing heat and detoxicating , moisten the skin and improve looks, relieve too much alcohol and tobacco.
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