Giant Knotweed Extract

Short Description:

Giant Knotweed Extract polydatin is the glycoside of resveratrol  isolated from the Chinese herb Polygonum cuspidatum.Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibitstherapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the directprotection of neurons.Polygonum is one of the plants of polygonaceae. It is native to east Asia and widely distributed in China. Knotweed is used in traditional Chinese and Japanese medicine to treat a variety of ailments, including fungal infections, skin inflammation, cardiovascular disease and liver disease.

Resveratrol and emodin are the main functional components of polygonum cuspidatum. Studies have shown that resveratrol and emodin exhibit a wide range of antioxidant properties, such as LDL cholesterol oxidation and lipid peroxidation. Resveratrol has also been shown to contribute to cardiovascular health and blood circulation, relieve pain, clear away heat, damp, poison and phlegm. Other ingredients including dananone, emodin methyl ether and rhein have anti-inflammatory, arthritic and antimicrobial activities.

Product Detail

Product Description

Product Name: Giant knotweed extract

Latin NamePolygonum Cuspidatum

CategoryPlant Extracts

Effective components: Resveratrol

Product specification50%, 98%

Analysis: HPLC

Quality Control : In House

Formulate: C14H12O3

Molecular weight: 228.25

CAS No501-36-0

Appearance: Off-white fine powder/off-white granule with characteristic odor.

Identification: Passes all criteria tests

Storage: keep in cool and dry place, well-closed, away from moisture or direct sunlight.

Volume Savings: Sufficient material supply and stable supply channel of raw material in north China.

Certificate of Analysis

Product name Giant knotweed extract Botanical Source Polygonum cuspidatum.
Batch NO. RW-GK20210508 Batch Quantity 1000 kgs
Manufacture Date May. 08. 2021 Inspection Date May. 17. 2021
Solvents Residue Water&Ethanol Part Used Root&Stam
Physical&Chemical Data
Color Off-White Organoleptic Qualified
Ordour Characteristic Organoleptic Qualified
Appearance Fine Powder Organoleptic Qualified
Analytical Quality
Identification Identical to R.S. sample HPTLC Identical
Assay(L-5-HTP) ≥98.0% HPLC 98.63%
Loss on Drying 5.0% Max. Eur.Ph.7.0 [2.5.12] 3.21%
Total Ash 5.0% Max. Eur.Ph.7.0 [2.4.16] 3.62%
Sieve 100% pass 80 mesh USP36<786> Conform
Loose Density 20~60 g/100ml Eur.Ph.7.0 [2.9.34] 53.38 g/100ml
Tap Density 30~80 g/100ml Eur.Ph.7.0 [2.9.34] 72.38 g/100ml
Solvents Residue Meet Eur.Ph.7.0 <5.4> Eur.Ph.7.0 <2.4.24> Qualified
Pesticides Residue Meet USP Requirements USP36 <561> Qualified
Heavy Metals
Total Heavy Metals 10ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS 1.388g/kg
Lead (Pb) 3.0ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS 0.062g/kg
Arsenic (As) 2.0ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS 0.005g/kg
Cadmium(Cd) 1.0ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS 0.005g/kg
Mercury (Hg) 0.5ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS 0.025g/kg
Microbe Tests
Total Plate Count NMT 1000cfu/g USP  <2021> Qualified
Total Yeast & Mold NMT 100cfu/g USP  <2021> Qualified
E.Coli Negative USP  <2021> Negative
Salmonella Negative USP  <2021> Negative
Packing&Storage Packed in paper-drums and two plastic-bags inside.
N.W: 25kgs
Store in a well-closed container away from moisture, light, oxygen.
Shelf life 24 months under the conditions above and in its original packaging.

Analyst: Dang Wang

Checked by: Lei Li

Approved by: Yang Zhang

Product Function

Resveratrol weight loss, Resveratrol is naturally occurring phytoalexin produced by some higher plants in response to injury or fungal in fection. Phytoalexins are chemical substances produced by plants as a defense against in faction by pathogenic microorganisms,Natural Resveratrol may also have alexin-like activity for humans. Epidemiological, in vitro and animal studies suggest that a high resveratrol  intake is associated with a reduced incidence of cardiovascular disease, and a reduced  risk for cancer.

Cardiovascular - Resveratrol decreases the viscosity of the blood and acts as anticoagulant to thin blood, effective in treating cardiovascular disease by reducing  thrombosis and embolisms that can block arteries and lead to myocardial and  cerebral infarctions.

Cancer - Resveratrol has been found to reduce tumor volume, tumor weight Weight Loss - resveratrol is the most potent natural compound mimicking the positive effect of calorie restriction.

Antioxidant resveratrol prevent aging by protecting cellular free-radical damage.

kill Lyme bacteria.  

Antimicrobial - To inhibit the growth of staph,salmonella the dosage. inhibit the growth of influ.


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