Short Description:

Anise Extract Shikimic Acid,which is our leading product,which has absolutely advantages in this field:

1, The Anise is pure natural.

3, Sufficient Shikimic Acid is ensured by Whole World Purchase System, Ghana is one base in Africa.

3, Sufficient Shikimic Acid stocks with all specifications,we have a competitive price based on excellent quality,bacause we are the factory,we are the source

Product Detail

Product Description

Product Name: Shikimic acid

Category: Plant Extracts

Effective components: Shikimic acid

Product specification: 98.0%

Analysis: HPLC

Quality Control: In House

Formulate: C7H10O5

Molecular weight: 174.15

CAS No: 138-59-0

Appearance: White Powder with characteristic odor.

Identification: Passes all criteria tests

Storage: Keep in cool and dry place, well-closed, away from moisture or direct sunlight.

Volume Savings: Sufficient material supply and stable supply channel of raw material.

Introduction of Shikimic acid

What is Shikimic Acid?

Shikimic acid (3,4,5-trihydroxy-1-cyclohexene-1-carboxylic acid) is a naturally occurring organic compound that is an important intermediate in the biosynthesis of lignin, aromatic amino acids (phenylalanine, tyrosine and tryptophan), and most plant and microbial alkaloids.

Shikimic acid is commonly used as a starting material for the industrial synthesis of the antiviral drug oseltamivir (an anti-H5N1 influenza virus drug used to treat and prevent all known strains of influenza viruses). The synthesis of (-)-zeylenone based on Shikimic Acid has been reported to be widely used as an agent for cancer chemotherapy. Data are available on the synthesis of monopalmitoyloxy Shikimic Acid, which has anticoagulant activity and is capable of reducing blood coagulability when administered intramuscularly. A Chinese research team synthesized a Shikimic Acid derivative, triacetyl Shikimic Acid, which exhibits anticoagulant and antithrombotic activity.

In addition, Shikimic Acid derivatives have shown great interest in agriculture as many of them are used as herbicides and antimicrobial agents because they can block the Shikimic Acid pathway in plants and bacteria without negatively affecting mammals.

Thus, Shikimic Acid can be used as a reactant for organic synthesis in both basic science and medical applications in organic chemistry and medicine, especially for the preparation of various drugs.

As an important pharmaceutical chemical material, shikimic acid can be applied to the treatment of many diseases:

1. Antibacterial and antitumor

In 1987, Japanese scholars found that the analog of glyoxalase I inhibitor synthesized by methyl anthranilate has obvious inhibitory effect on Hela cell line and Escheri ascites carcinoma, can prolong the survival time of mice inoculated with leukemia cell L1210, and the toxicity is relatively low, its inhibitory effect is mainly related to the sulfur hydride reaction. 1988, Chinese scholars have In 1988, Chinese scholars have synthesized a shikimic acid derivative and proved that this compound has the effect of inhibiting leukemia cells L1210 in vitro.

2. Anti-thrombosis

The effect of shikimic acid and its derivatives on cardiovascular system is shown in the role of anti-thrombosis and inhibition of platelet aggregation. Research shows that: shikimic acid has a strong inhibitory effect on the platelet aggregation rate of adenosine diphosphate-induced middle cerebral artery embolism model rats; intravenous and intramuscular injection of shikimic acid can make the blood clotting time of mice prolonged.

3.Anti-cerebral ischemia

Shikimic acid and its derivatives have the effect of improving cerebral ischemia, mainly in reducing the volume of cerebral infarction after focal cerebral ischemia in rats, reducing the neurological function score, reducing the degree of cerebral edema, increasing the cerebral blood flow in the ischemic area and other indicators. Some studies have shown that its derivatives can reduce the degree of erythrocyte aggregation and inhibit platelet aggregation after cerebral ischemia, thus facilitating cerebral microcirculation.

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Certificate of Analysis

Product name Shikimic acid Botanical Source Shikimic acid
Batch NO. RW-SA20210322 Batch Quantity 1100 kgs
Manufacture Date May. 22. 2021 Expiration Date May. 27. 2021
Solvents Residue Water&Ethanol Part Used Fruit
Physical&Chemical Data
Color White Organoleptic Qualified
Ordour Characteristic Organoleptic Qualified
Appearance Powder Organoleptic Qualified
Analytical Quality
Identification Identical to R.S. sample HPTLC Identical
Assay ≥98.0% HPLC Qualified
Loss on Drying 2.0% Max. Eur.Ph.7.0 [2.5.12] Qualified
Total Ash 0.5% Max. Eur.Ph.7.0 [2.4.16] Qualified
Sieve 100% pass 80 mesh USP36<786> Conform
Solvents Residue Meet Eur.Ph.7.0 <5.4> Eur.Ph.7.0 <2.4.24> Qualified
Pesticides Residue Meet USP Requirements USP36 <561> Qualified
Heavy Metals
Total Heavy Metals 10ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS Qualified
Lead (Pb) 2.0ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS Qualified
Arsenic (As) 2.0ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS Qualified
Cadmium(Cd) 1.0ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS Qualified
Mercury (Hg) 1.0ppm Max. Eur.Ph.7.0 <2.2.58> ICP-MS Qualified
Microbe Tests
Total Plate Count NMT 1000cfu/g USP  <2021> Qualified
Total Yeast & Mold NMT 100cfu/g USP  <2021> Qualified
E.Coli Negative USP  <2021> Negative
Salmonella Negative USP  <2021> Negative
Packing&Storage   Packed in paper-drums and two plastic-bags inside.
N.W: 25kgs
Store in a well-closed container away from moisture, light, oxygen.
Shelf life 24 months under the conditions above and in its original packaging.

Analyst: Dang Wang

Checked by: Lei Li

Approved by: Yang Zhang

Product Function

Shikimic Acid Structure inhibits platelet aggregation, inhibits the formation of arterial and venous thrombosis and cerebral thrombosis;anti-inflammatory and analgesic effects;Be used as an antiviral and anticancer drug intermediate,should not be used directly.


1, Star Anise Shikimic Acid uses inhibit platelet aggregation.

2, Inhibit arterial and venous thrombosis and cerebral thrombosis.

3, Antiviral and anticancer drug intermediates.

4, Anti-inflammatory and analgesic effects.

5, At present, shikimic acid is mainly used as one of the main raw materials for the synthetic treatment of bird flu drug-Tamiflu.

6, Pharmaceutical stuff;Functional food and food additive;Cosmetics additive.


About natural plant extract, contact us at info@ruiwophytochem.com at any time! We are a professional Plant Extract Factory, which has three production bases!

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